Jumat, 13 Februari 2015

Multiple Sclerosis


Multiple Sclerosis (MS), is a neurological disorder that can affect nearly every system of the body, which is controlled by nerves. It is a disease that can be present in the episode or can be rapidly progressive. The main cause is de-myelinization of the nerve sheath in the brain and in the spinal cord.

The most common symptoms are paresis (muscle weakness), seizures, paralysis, blindness due to optic neuritis, urinary incontinence, bowel movements disturbed by alternating diarrheoa and constipation, memory loss, etc. Most of the signs and symptoms seen in the episode, when Remission and Relapse refers. It's just as dawn or dusk phenomenon. During the episode the patient is able to face the dark night because of blindness, while during remission which is free episodes of symptoms, the patient is completely normal and have a sunny day in the life. The patients were evaluated by the Expanded Disability Status Score (EDSS) score dysability.

On top of all of life of MS patients is a daily battle. Symptoms may worsen with increasing the size of the lesion de-myelinizating myelin sheath in the brain MRI.

This treatment has not been another challenge. Despite recent advances in the science, until now still can not be treated MS enemy. Treatments available in the market can only slowly or seize further worsening of symptoms, but still no cure found yet, is intended to fully cure this devastating disease. In addition to the route of administration is also painful. With most drugs are likely to manage only through injection route, such as Glatiramer acetate (Copaxone) is given by sub-cutaneous injections per day with one and intra-muscular interferon given three days a week. A better option is natalizumab (Tysabri), is given only once in 28 days via the intravenous route. With the recent advances oral therapy was introduced in the market, but hardly available in most countries.

A strong will of the patient can do wonders, can not only improve the quality of life with a positive, but also can improve symptoms to a greater extent. Patient awareness program and encourage activities can help better the lives of patients suffering from MS. The more patients know about their disease, the more help they can give to themselves. In today's world, where the internet plays an important role in everyday life, the patient would like to read more about their disease, as well as reading the article the different experiences of other patients suffering from the same disease worldwide. Therefore, the forum should be encouraged and more and more e-materials shall be provided. Support from family and friends can further facilitate the work of neuro-physiscians in helping patients live a quality life.

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