Burkitts lymphoma
is a very rare type of cancer. Less than a thousand cases diagnosed each year
in the United States.
However, in some other parts of the world where it is
endemic, such as certain parts of Central Africa, Burkitt's lymphoma is very
common among children.
Burkitt's lymphoma is Non-Hodgkin Lymphoma (NHL) cancer that
affects lymphocytes B. There are three different types of this disease:
Related -Immunodeficiency: Forms condition occurs most
frequently in HIV patients and immunocompromised individuals such as transplant
recipients same recently. This condition may signal the onset of AIDS.
-Sporadic: This is a variant of the disease is found outside
the African continent. It is similar to endemic Burkitt's lymphoma and is
associated with compromised immune systems.
-Endemic: This form of the disease called
"African" form and is responsible for most cases of malignant central
African children. Form of the disease may affect some areas but most often
impacts jaw, ovarian, breast, kidney, facial bones. Epstein-Barr virus, which
is the virus responsible for mononucleosis is closely associated with Burkitt.
Burkitts lymphoma Symptoms may include pain, swelling of the
lymph nodes (this is the characteristic of lymphoma in general), hardening and
/ or the rapid growth of the lymph nodes. Pain in the abdomen is another
possible sign.
This disease can be diagnosed by various modes such as:
-X-Ray chest
-Blood Counts
Fluid analysis -Spinal
-Lymph Node and / or bone marrow biopsy
-CT and / or PET Scan
Treatment of this disease usually involves intense
chemotherapy. Before that chemotherapy is started, the better the prospects
because this is a very aggressive form of cancer. However, some fast-growing
cancers such as Burkitt, respond more quickly to treatment. It can actually harm
the patient through a process called lysis syndrome tumor, in which the body is
exposed byproduct of the breakdown of cancer cells that can cause one of a
number of serious complications such as severe electrolyte disturbances and
kidney failure.
Combination chemotherapy can be equipped with radiotherapy,
dietary interventions, nootropics, supplements, exposure to natural sunlight
(vitamin D). Surgery is often indicated to remove the tumor and bone marrow
transplantation may be required in the case that the bone marrow is affected.
Burkitt's lymphoma prognosis depends on patient risk
factors. Caught early (low risk or low / intermediate risk), combination
chemotherapy has resulted in survival rates in the range of 90%. These figures
decreased significantly for high-risk cases; ~ 70% for the medium risk / high
and ~ 30% for high risk. Total 5-year survival rate for adults with Burkitts
lymphoma is approximately 50 percent.
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